PF 431396

CAS No. 717906-29-1

PF 431396 ( PF-431396; PF 431396; PF431396 )

Catalog No. M19031 CAS No. 717906-29-1

PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 In Stock
10MG 67 In Stock
25MG 133 In Stock
50MG 235 In Stock
100MG 402 In Stock
200MG 593 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PF 431396
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
  • Description
    PF-431396 is a potent and selective focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively).
  • Synonyms
    PF-431396; PF 431396; PF431396
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    FAK; PYK2
  • Research Area
    Endocrinology
  • Indication
    ——

Chemical Information

  • CAS Number
    717906-29-1
  • Formula Weight
    506.5
  • Molecular Formula
    C22H21F3N6O3S
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    n1c(nc(c(c1)C(F)(F)F)NCc1c(cccc1)N(C)S(=O)(=O)C)Nc1ccc2c(c1)CC(=O)N2
  • Chemical Name
    N-Methyl-N-[2-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]methanesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Han S, et al. J Biol Chem. 2009, 284(19), 13193-13201.
molnova catalog
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